THE 2-MINUTE RULE FOR 8-HYDROXY-2'-DEOXYGUANOSINE

During this report, we executed an entire protein-coding genome RNA interference (RNAi) screen to determine possible targets whose inhibition can enhance the efficacy of CX-5461 in treating HR-proficient HGSC. We show the CX-5461 exhibits a singular sensitivity pattern distinctive to People documented for G-quadruplex stabilisers and topoisomerase